06-04-2025
Stomatitis, also known as oral mucositis, refers to inflammation of the tissue lining the mouth or lips. Common forms include cold sores and canker sores. It can be caused by infections, physical injuries, allergic reactions, or side effects of cancer treatments. Addressing the root cause typically resolves the inflammation, while medications can help relieve symptoms in the meantime. In this article, we will discuss the causes of stomatitis as well as common types of the condition, symptoms, and treatment methods.
Key Takeaways
- There are several different types of stomatitis, each of which have different symptoms, causes and treatments, so it’s important you are properly diagnosed.
- There are at-home remedies to soothe the pain and heal stomatitis. If the condition persists, seek medical help.
- Poor oral hygiene can trigger as well as prolong the symptoms of stomatitis. Good oral hygiene includes brushing twice daily, flossing, and using an antimicrobial mouthwash.
What is Stomatitis?
Stomatitis is a generic term that refers to the inflammation of mucosa tissues inside your mouth and on your lips. There are several types of stomatitis, the most common (and familiar) being cold sores and canker sores.
Stomatitis can happen anywhere within the mouth and can be painful and disrupt our eating and drinking habits.
Types of Stomatitis
If you are living with stomatitis, it is important that you can discern which type of the condition affects you so you can seek adequate treatment. The most common types of stomatitis include:
Aphthous Stomatitis (Canker Sores)
One of the most common types of stomatitis is aphthous stomatitis, more commonly referred to as canker sores or mouth ulcers. Canker sores are spherical red or white lesions that form within the mouth. They are often painful or uncomfortable and can make eating and drinking more difficult.
If you are wondering what causes mouth ulcers, then it will typically be:
Stress and fatigue
Vitamin deficiencies
Hormonal changes
Canker sores are not contagious, so unlike some other types of stomatitis, when living with mouth ulcers you will not need to avoid close contact with others.
Herpetic Stomatitis (Cold Sores / Oral Herpes)
Another common type of stomatitis is herpetic stomatitis, also known as cold sores or oral herpes. Cold sores are caused by Herpes Simplex virus (HSV-1) and appear as small fluid-filled blisters on the lips, gums, or tongue.
If it is your first time experiencing one, oral herpes symptoms can include fever, headaches and even nausea. During reoccurrences of the virus, a person may feel a tingling sensation before a blister forms, then pain or discomfort once it has formed.
Cold sores are highly contagious. If you are living with herpetic stomatitis, avoid close contact with others, especially children, as HSV-1 is particularly dangerous for young people.
Angular Cheilitis (Cracked Corners of the Mouth)
Angular cheilitis is a fairly common skin condition that affects the corners of the mouth. It occurs when saliva builds up at the corners of the mouth and dries out the skin, eventually leading to painful cracks around the mouth and lips.
Angular cheilitis can also be caused by bacterial or fungal infections, vitamin deficiencies, and eczema. Most cases of the condition are not serious, but cracks around the mouth can be painful and irritating. Angular cheilitis treatment can be as simple as topical creams, but depending on the severity of the condition antibiotics or dental work may be needed.
Denture Stomatitis
If you wear dentures, you may occasionally notice inflammation or tenderness within your mouth. Denture stomatitis is a common condition, and type of thrush, that affects tissue within your mouth. Symptoms of denture stomatitis include:
Canker sores
Angular Cheilitis
Red/white patches within the mouth
Soreness within the mouth
One of the main causes of denture stomatitis is poor oral hygiene meaning it is vital to clean your teeth and mouth adequately if you wear dentures. Denture stomatitis treatment may involve antifungal medications, laser therapy, or oral surgeries in extreme cases.
Allergic Contact Stomatitis
Allergies and intolerances can also cause stomatitis. If the mouth comes into contact with an allergen, you may experience burning, swelling, or inflammation within the mouth. Toothpaste, mouthwash, and other commonly used oral hygiene products are often responsible for contact stomatitis, so if you experience the condition consider changing your oral care products.
Symptoms of Stomatitis
There are several reasons why a person may experience stomatitis and symptoms of the condition vary depending on the underlying cause. Among the various types of stomatitis, the most common symptoms include:
Mouth Sores (ulcers, blisters, red/white patches)
Pain in the mouth including a burning sensation
Swelling and redness in the mouth
Difficulty eating or speaking
Causes of Stomatitis
There are several causes of stomatitis, some more common than others. Causes of the condition can include:
Mouth trauma including burns, surgical damage, and biting the tongue or cheek
Bacterial infections (often stemming from poor oral hygiene)
Fungal infections
Viral infections (including HSV-1)
Nutritional deficiencies, namely Vitamin B12, iron, and folic acid
Autoimmune diseases including Crohn’s and lupus
Allergic reactions
Irritating foods
How to Treat Stomatitis
Several stomatitis treatment methods can effectively tackle the condition. Both at-home, over the counter, and medical procedures can help alleviate and cure the condition.
Home Remedies for Stomatitis Relief
If you are experiencing a mild case of stomatitis, then it is advisable to try out stomatitis home remedies before seeking professional help. Common at-home treatment methods for stomatitis include:
Saline (salt water) rinses: Rinsing the mouth with salt water or a saline solution can calm inflammation and reduce pain
Baking soda rinses: Baking soda can neutralise harmful acid within the mouth and help sore areas heal
Honey: A natural antibacterial and anti-inflammatory, honey can ease the pain of stomatitis and help treat soreness
Aloe vera gel: Helps soothe sores
Dietary changes: Acidic, spicy, and rough foods can all worsen stomatitis so avoiding these is important when living with the condition
If you try these and are still left wondering ‘what is the best treatment for stomatitis’, then it may be time to try more serious treatments such as OTC medication or seek professional help.
Over-the-Counter Medications
Several OTC medications can offer effective stomatitis treatment including:
Antiseptic mouthwashes: Prescription mouthwashes can ease the pain of mouth sores and reduce the chances of their recurrence
Pain relieving creams: Can ease the pain of severe sores and reduce the temptation to touch them – helping the healing process
Hydrogen peroxide rinses: Act as a mild antiseptic which eases irritation by removing mucus and cleaning the mouth
Antihistamines or corticosteroids: In severe cases, these can be used to reduce inflammation
Medical Treatments
In cases where neither at-home nor OTC stomatitis treatments work, it may be necessary to seek medical attention. Your doctor can help with persistent or unpleasant stomatitis cases with one of the following treatment methods:
Antiviral medications: If herpes is the cause of your stomatitis, then your doctor may prescribe an antiviral medication to treat it. While HSV-1 cannot be cured, medications can ease symptoms and stop pain making it one of the best cold sore-in-mouth treatments.
Antifungal treatments: For denture stomatitis treatment a doctor may prescribe antifungal medications. These can treat thrush effectively, eradicating the condition and curing stomatitis.
Antibiotics: If a bacterial infection is the cause of stomatitis, then you will likely need antibiotics, these can cure your infection and stomatitis.
Steroid treatments: For autoimmune-related stomatitis (conditions such as eczema) you may need steroid creams and treatments to reduce the effects of stomatitis and calm symptoms.
How to Prevent Stomatitis
Though not all types of stomatitis can be completely prevented, there are several ways in which you can reduce the likelihood of the condition occurring. One of the most important preventative measures is a balanced diet, vitamin deficiencies are a common cause of stomatitis and can be avoided by eating a nutrient-rich diet. Staying hydrated will also help as it can prevent the type of dry mouth that causes angular cheilitis.
Maintaining good oral health is vital when trying to prevent stomatitis. Using products that both protect and clean the mouth is the best way to do this, as you can avoid trauma that can cause stomatitis.
When to See a Doctor
At a certain point, it may be necessary to see a doctor about your stomatitis. If any of the following apply to your case, then you should seek medical attention:
Stomatitis that lasts more than 2 weeks
Sores that are large, extremely painful or spreading
Fevers or difficulty swallowing
Swollen lymph nodes
Frequently reoccurring stomatitis
Stomatitis Prevention Starts with a Great Oral Hygiene Routine
No matter the cause, the symptoms of stomatitis (oral mucositis) can be uncomfortable. Sores, blisters, and other signs may also affect your confidence. The good news is that the discomfort often improves over time.
Depending on the underlying cause, over the counter or prescription treatments may help speed up healing. If you have a sore that isn't healing or you're noticing other symptoms, it's a good idea to check in with your healthcare provider. They can identify the cause and recommend effective treatment options.
While stomatitis can be painful and impact your confidence, a consistent and effective oral care routine plays a key role in prevention and recovery. That’s why Oral-B champions the importance of daily oral hygiene — and the Oral-B iO Series electric toothbrushes are at the heart of that mission. Designed to be both gentle and powerful, the iO Series supports gum and oral health.
FAQs
Can poor oral hygiene cause stomatitis?
How can good oral hygiene help prevent stomatitis?
Should I continue brushing if I have stomatitis?
When should I see a doctor or dentist for stomatitis?
Sources
https://my.clevelandclinic.org/health/diseases/stomatitis-oral-mucositis
https://www.webmd.com/oral-health/stomatitis-causes-treatment
https://www.nhsinform.scot/illnesses-and-conditions/mouth/cold-sore
https://my.clevelandclinic.org/health/diseases/21470-angular-cheilitis
https://my.clevelandclinic.org/health/diseases/21702-denture-stomatitis
https://www.verywellhealth.com/stomatitis-overview-4584883#toc-stomatitis-treatment
https://www.webmd.com/drugs/2/drug-4570/hydrogen-peroxide-mucous-membrane/details
About Our Medical Reviewers
Dr Robert Lee is a dentist with more than thirty years of experience in the industry. Graduating from the University of Sydney with a Bachelor of Dental Surgery and from the University of New South Wales with a Master of Business Administration, Robert’s career has taken him all over the world – from Australia to Germany to his current position in Chicago, where he is the founder of Denticus Inc., offering strategic dental consulting. Robert has previously worked for Procter & Gamble as the Director of Professional Scientific Relations in both the Cincinnati and Sydney offices, being responsible for external relations and scientific exchange with leading professional associations and industry thought leaders. He was also responsible for all technical and scientific training for the professional teams in North America and Australia. Robert has been assisting the team at Oral-B by fact-checking and reviewing our blogs on dental health.
Table of Contents

Sign Up
for expert advice and exclusive offers
